产品货号：
Z38499
中文名称：
HCK抗体
英文名称：
Anti-HCK Antibody (Clone#1508CT602.13.1)
产品规格：
50μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HCK Antibody (Clone#1508CT602.13.1) |
| 指标别名 | HCK,hemopoietic cell kinase,JTK9,p59 HCK/p60 HCK,Tyrosine protein kinase HCK |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,IF |
| 基因名称 | HCK |
| 克隆号 | 1508CT602.13.1 |
| 抗体来源 | Mouse |
| 免疫原 | This HCK antibody is generated from a mouse immunized with a recombinant protein of human HCK. |
| 计算分子量 | 60kDa |
| 成分 | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein G column,followed by dialysis against PBS |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Non-receptor tyrosine-protein kinase found in hematopoietic cells that transmits signals from cell surface receptors and plays an important role in the regulation of innate immune responses,including neutrophil,monocyte,macrophage and mast cell functions,phagocytosis,cell survival and proliferation,cell adhesion and migration.Acts downstream of receptors that bind the Fc region of immunoglobulins,such as FCGR1A and FCGR2A,but also CSF3R,PLAUR,the receptors for IFNG,IL2,IL6 and IL8,and integrins,such as ITGB1 and ITGB2.During the phagocytic process,mediates mobilization of secretory lysosomes,degranulation,and activation of NADPH oxidase to bring about the respiratory burst.Plays a role in the release of inflammatory molecules.Promotes reorganization of the actin cytoskeleton and actin polymerization,formation of podosomes and cell protrusions.Inhibits TP73-mediated transcription activation and TP73-mediated apoptosis.Phosphorylates CBL in response to activation of immunoglobulin gamma Fc region receptors.Phosphorylates ADAM15,BCR,ELMO1,FCGR2A,GAB1,GAB2,RAPGEF1,STAT5B,TP73,VAV1 and WAS. |
| Uniprot ID | P08631 |
相关搜索：HCK抗体，HCK单抗，Anti-HCK Antibody (Clone#1508CT602.13.1)